Depends on what im playing vs what they are playing.
Lock vs Barb, lock wins almost every time, esp if they throw in some mental and see each other at the same time. Meteor, lightning, will domain, magma blast, ivy, meteor, fireball, dead.
Warju, well fight with warju is almost always death for any class.
Hunters are not a lot of problem, esp on my lock, the only issue is that they always manage to get away as that 20% base speed boost really helps to up their %speed increase.
Marks....never had a lot of trouble with them, on any class.
Knight vs Lock, i die a lot vs knight, lots of resist and block means vital spells that i rely on dont go through and i die...oh and shield bash
Barb, i dont have a lot of trouble with barbs, on any class, but it may be from positioning lag too.
Normal conj...if they are in a poor enough situation to be alone, they are usually easy prey, but even with one other member defending them, almost impossible.
Lag + Positioning lag, never managed to pvp it with any success.